iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain Zn_dep_PLPC

Zn_dep_PLPC

Zinc dependent phospholipase C (alpha toxin)

Zn_dep_PLPC
SMART accession number:SM000770
Description:This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.

Pathways containing proteins with Zn_dep_PLPC domain are shown in BLUE, and edges containing orthologs which have Zn_dep_PLPC domain are shown in RED.