iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain ZnF_ZZ


Zinc-binding domain, present in Dystrophin, CREB-binding protein.

SMART accession number:SM000291
Description:Putative zinc-binding domain present in dystrophin-like proteins, and CREB-binding protein/p300 homologues. The ZZ in dystrophin appears to bind calmodulin. A missense mutation of one of the conserved cysteines in dystrophin results in a patient with Duchenne muscular dystrophy [3].

Pathways containing proteins with ZnF_ZZ domain are shown in BLUE, and edges containing orthologs which have ZnF_ZZ domain are shown in RED.