iPath: Interactive Pathways Explorer
Metabolic pathways map for SMART domain UBCc
UBCcUbiquitin-conjugating enzyme E2, catalytic domain homologues | ||
SMART accession number: | SM000212 | |
---|---|---|
Description: | Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologues. This pathway functions in regulating many fundamental processes required for cell viability.TSG101 is one of several UBC homologues that lacks this active site cysteine. |
Pathways containing proteins with UBCc domain are shown in BLUE, and edges containing orthologs which have UBCc domain are shown in RED.