iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain UBCc


Ubiquitin-conjugating enzyme E2, catalytic domain homologues

SMART accession number:SM000212
Description:Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologues. This pathway functions in regulating many fundamental processes required for cell viability.TSG101 is one of several UBC homologues that lacks this active site cysteine.

Pathways containing proteins with UBCc domain are shown in BLUE, and edges containing orthologs which have UBCc domain are shown in RED.