iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain SH2


Src homology 2 domains

SMART accession number:SM000252
Description:Src homology 2 domains bind phosphotyrosine-containing polypeptides via 2 surface pockets. Specificity is provided via interaction with residues that are distinct from the phosphotyrosine. Only a single occurrence of a SH2 domain has been found in S. cerevisiae.

Pathways containing proteins with SH2 domain are shown in BLUE, and edges containing orthologs which have SH2 domain are shown in RED.