iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain RA


Ras association (RalGDS/AF-6) domain

SMART accession number:SM000314
Description:RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Kalhammer et al. have shown that not all RA domains bind RasGTP. Predicted structure similar to that determined, and that of the RasGTP-binding domain of Raf kinase. Predicted RA domains in PLC210 and nore1 found to bind RasGTP. Included outliers (Grb7, Grb14, adenylyl cyclases etc.)

Pathways containing proteins with RA domain are shown in BLUE, and edges containing orthologs which have RA domain are shown in RED.