iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain PLCYc


Phospholipase C, catalytic domain (part); domain Y

SMART accession number:SM000149
Description:Phosphoinositide-specific phospholipases C. These enzymes contain 2 regions (X and Y) which together form a TIM barrel-like structure containing the active site residues. Phospholipase C enzymes (PI-PLC) act as signal transducers that generate two second messengers, inositol-1,4,5-trisphosphate and diacylglycerol. The bacterial enzyme [6] appears to be a homologue of the mammalian PLCs.

Pathways containing proteins with PLCYc domain are shown in BLUE, and edges containing orthologs which have PLCYc domain are shown in RED.