iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain LisH


Lissencephaly type-1-like homology motif

SMART accession number:SM000667
Description:Alpha-helical motif present in Lis1, treacle, Nopp140, some katanin p60 subunits, muskelin, tonneau, LEUNIG and numerous WD40 repeat-containing proteins. It is suggested that LisH motifs contribute to the regulation of microtubule dynamics, either by mediating dimerisation, or else by binding cytoplasmic dynein heavy chain or microtubules directly.

Pathways containing proteins with LisH domain are shown in BLUE, and edges containing orthologs which have LisH domain are shown in RED.