iPath: Interactive Pathways Explorer
Metabolic pathways map for SMART domain LisH
LisHLissencephaly type-1-like homology motif | ||
SMART accession number: | SM000667 | |
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Description: | Alpha-helical motif present in Lis1, treacle, Nopp140, some katanin p60 subunits, muskelin, tonneau, LEUNIG and numerous WD40 repeat-containing proteins. It is suggested that LisH motifs contribute to the regulation of microtubule dynamics, either by mediating dimerisation, or else by binding cytoplasmic dynein heavy chain or microtubules directly. |
Pathways containing proteins with LisH domain are shown in BLUE, and edges containing orthologs which have LisH domain are shown in RED.