iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain Lactamase_B


Metallo-beta-lactamase superfamily

SMART accession number:SM000849
Description:Apart from the beta-lactamases a number of other proteins contain this domain PUBMED:7588620. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.

Pathways containing proteins with Lactamase_B domain are shown in BLUE, and edges containing orthologs which have Lactamase_B domain are shown in RED.