iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain EFh


EF-hand, calcium binding motif

SMART accession number:SM000054
Description:EF-hands are calcium-binding motifs that occur at least in pairs. Links between disease states and genes encoding EF-hands, particularly the S100 subclass, are emerging. Each motif consists of a 12 residue loop flanked on either side by a 12 residue alpha-helix. EF-hands undergo a conformational change unpon binding calcium ions.

Pathways containing proteins with EFh domain are shown in BLUE, and edges containing orthologs which have EFh domain are shown in RED.