iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain DEP


Domain found in Dishevelled, Egl-10, and Pleckstrin

SMART accession number:SM000049
Description:Domain of unknown function present in signalling proteins that contain PH, rasGEF, rhoGEF, rhoGAP, RGS, PDZ domains. DEP domain in Drosophila dishevelled is essential to rescue planar polarity defects and induce JNK signalling (Cell 94, 109-118).

Pathways containing proteins with DEP domain are shown in BLUE, and edges containing orthologs which have DEP domain are shown in RED.