iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain CBS


Domain in cystathionine beta-synthase and other proteins.

SMART accession number:SM000116
Description:Domain present in all 3 forms of cellular life. Present in two copies in inosine monophosphate dehydrogenase, of which one is disordered in the crystal structure [3]. A number of disease states are associated with CBS-containing proteins including homocystinuria, Becker's and Thomsen disease.

Pathways containing proteins with CBS domain are shown in BLUE, and edges containing orthologs which have CBS domain are shown in RED.