iPath: Interactive Pathways Explorer
Metabolic pathways map for SMART domain C2
C2Protein kinase C conserved region 2 (CalB) |  | |
| SMART accession number: | SM000239 | |
|---|---|---|
| Description: | Ca2+-binding motif present in phospholipases, protein kinases C, and synaptotamins (among others). Some do not appear to contain Ca2+-binding sites. Particular C2s appear to bind phospholipids, inositol polyphosphates, and intracellular proteins. Unusual occurrence in perforin. Synaptotagmin and PLC C2s are permuted in sequence with respect to N- and C-terminal beta strands. SMART detects C2 domains using one or both of two profiles. | |
Pathways containing proteins with C2 domain are shown in BLUE, and edges containing orthologs which have C2 domain are shown in RED.
