iPath: Interactive Pathways Explorer

Metabolic pathways map for SMART domain BATS


Biotin and Thiamin Synthesis associated domain

SMART accession number:SM000876
Description:Biotin synthase (BioB), , catalyses the last step of the biotin biosynthetic pathway. The reaction consists in the introduction of a sulphur atom into dethiobiotin. BioB functions as a homodimer PUBMED:12482614. Thiamin synthesis if a complex process involving at least six gene products (ThiFSGH, ThiI and ThiJ). Two of the proteins required for the biosynthesis of the thiazole moiety of thiamine (vitamin B(1)) are ThiG and ThiH (this entry) and form a heterodimerPUBMED:12650933. Both of these reactions are thought of involve the binding of co-factors, and both function as dimers PUBMED:12482614, PUBMED:12650933. This domain therefore may be involved in co-factor binding or dimerisation.

Pathways containing proteins with BATS domain are shown in BLUE, and edges containing orthologs which have BATS domain are shown in RED.